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Scott Shannon, MD, assistant clinical professor at the University of Colorado, recently sifted through patient charts from his four-doctor practice to document CBD’s effects on anxiety. His study, as yet unpublished, found “a fairly rapid decrease in anxiety scores that appears to persist for months,” he says. But he says he can’t discount a placebo effect, especially since “there’s a lot of hype right now.”
The CB1 receptors are mostly present in the brain, but some are located throughout your body. These receptors deal with movement and coordination, emotions, thinking, memories, pain, mood, appetite, and other function. The CB2 receptors are mostly in the immune system. They affect pain and inflammation. CBD works in two ways. It attaches itself to these receptors while stimulating the body to produce more cannabinoids on its own naturally. Amazingly, CBD assists the body in learning to heal itself.
To ship or not to ship, that is the question. And the answer isn’t as clear as you may think (or hope). Legally, there is still quite a bit of gray area surrounding shipping cannabis oil. Some experts say shipping is illegal and may result in confiscation and seizure, while others argue the Farm Act of 2018 makes buying, selling and shipping CBD oil perfectly legal, particularly if the CBD oil is hemp-derived. The DEA itself has stated that CBD is not a top priority for the agency.  

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Furthermore, a study published in the Journal of Neuroendocrinology has suggested that the ECS is capable of stimulating specific areas of the body involved in metabolism, such as the skeletal muscles and GI tract. This happens due to the presence of anandamide and 2-AG, which are two naturally-occurring compounds in the body that interact with the CB1 and CB2 receptors.
All in all, current research shows us that we will experience the most significant degree of therapeutic relief when all the cannabinoids and the terpenes —  essential oils that produce the plant’s aromas —  are in the oil. Even adding just a little THC in CBD oil can greatly improve the medical properties because of the phenomenon known as the entourage effect.
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