The endocannabinoid system is found in all mammals, and is made up of millions of cannabinoid receptor sites (CB1 and CB2 receptors) located throughout the body. The endocannabinoid system is one of the regulatory systems in the human body, but most people do very little to support the health of this system, because cannabinoids have not been part of the average diet. If you would like to know more about the technical aspects of the endocannabinoid system, you can go here.
While Hemp CBD oil has skyrocketed in popularity, it will hit the mainstream in 2019 as the few barriers holding it back are going the way of the Dodo. Within the next two to three years, we will see waves of clinical in-vivo research pouring in, and it will be fascinating to see if we discover anything new about the molecules that make up the oil and the plants themselves.

Even as we witness the unrelenting growth of the hemp and cannabis markets across the U.S., most legal aspects of the industry continue to be shrouded in veritable shades of gray. Federal lawmakers remain stubborn in removing cannabidiol (CBD) from the DEA’s list of Controlled Substances, even though the compound has recently been approved by the FDA to treat two rare forms of epilepsy.
Our bodies are thought to produce endocannabinoids by the billions every day. “We always thought the ‘runner’s high’ was due to the release of dopamine and endorphins. But now we know the euphoria is also from an endocannabinoid called anandamide,” its name derived from the Sanskrit word for bliss, says Joseph Maroon, MD, clinical professor and vice chairman of neurosurgery at the University of Pittsburgh Medical Center. We produce these natural chemicals all day, but they fade quickly because enzymes pop up to destroy them. That’s where CBD comes in: By blocking these enzymes, CBD allows the beneficial compounds to linger.
All in all, current research shows us that we will experience the most significant degree of therapeutic relief when all the cannabinoids and the terpenes —  essential oils that produce the plant’s aromas —  are in the oil. Even adding just a little THC in CBD oil can greatly improve the medical properties because of the phenomenon known as the entourage effect.
“Buying from a reputable manufacturer is crucial, because it matters how the plant is cultivated and processed,” Dr. Maroon says. One clue that a company is cutting corners: too low a cost. Good CBD is pricey—a bottle of high-quality capsules is sold in Cohen’s office for $140. But for many, it’s worth the money. Roth spent $60 on her tiny bottle. But when her energy returned the day she started taking CBD, she decided that was a small price to pay.
 Populum’s CBD oil utilizes a full-spectrum of cannabinoids. It has a subtle orange flavor and contains antioxidants, natural ingredients, and neuroprotectants. It is free from GMOs and gluten. The label shows that this product is made with several oils in addition to hemp oil, including grapeseed, orange, and virgin coconut oils. It also contains stevia extract for a sweet flavor.
But isn’t that because we are more willing to break our laws? Think about it. Saudi Arabia, for example, has much stricter laws than we do governing every aspect of life. Why aren’t they and countries like them the #1 incarcerators? I’m thinking either because their citizens are more law abiding by nature or are just plain scared of the barbaric punishments.
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