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Hemp CBD is completely different from cannabis CBD. Hemp also derives from the Cannabis sativa L plant, and while it also contains THC, it contains it in volumes that are less than 0.3% by dry weight. Some governments, including the US, regulate the concentration of THC and permit a specific variety of hemp (called industrial hemp) that is bred with an especially low THC content. This is the reason why, when you type into Google “CBD oil for Sale”, you get hundreds of companies trying to sell you their products – according to most all of them, CBD oil from industrial hemp is 100% legal to sell online and ship to all 50 states.
Researchers at the Department of Pharmacognosy, The School of Pharmacy, University of London, UK, basis the study conducted on mice found that CBD oil has analgesic properties and may relieve chronic pain of all kinds . It can disrupt the activity of pain receptors in the body and instead cause a release of neurotransmitters such as serotonin and dopamine – “feel good” compounds that can ease discomfort and pain, even if the pharmaceutical painkillers have no effect.
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But because all these products are illegal according to the federal government, cannabis advocates are cautious. “By and large, the federal government is looking the other way,” says Paul Armentano, deputy director of the Washington, DC–based National Organization for the Reform of Marijuana Laws (NORML), but until federal laws are changed, “this administration or a future one could crack down on people who produce, manufacture, or use CBD, and the law would be on its side.”


Over the past few years, increasing public and political pressure has supported legalization of medical marijuana. One of the main thrusts in this effort has related to the treatment of refractory epilepsy—especially in children with Dravet syndrome—using cannabidiol (CBD). Despite initiatives in numerous states to at least legalize possession of CBD oil for treating epilepsy, little published evidence is available to prove or disprove the efficacy and safety of CBD in patients with epilepsy. This review highlights some of the basic science theory behind the use of CBD, summarizes published data on clinical use of CBD for epilepsy, and highlights issues related to the use of currently available CBD products.
With all of the information inundating the internet about CBD oil, many people are curious, can CBD help with weight loss? A study done in 2012 documented the way that cannabinol and cannabidiol affected the feeding patterns in rats. After dosing rats with CBD, the scientists observed that they ate less; this set the stage for more research to be done to continue to show the weight loss opportunities with CBD. It also brought into light a new use for CBD as an appetite suppressant. In addition to that, a report in India Times in 2016 said that cannabis users show a lower rate of obesity and diabetes. Science has also demonstrated links between the use of cannabis and metabolism for many years.
This is likely why CBD is capable of stimulating appetite among people that are in dire need of nutrition (such as cancer patients on chemotherapy), while at the same time suppressing appetite in those who need to lose weight. The active compound helps keep the body in balance, so if you need weight gain it can help you eat, but if you are overweight, it may be able to help curb your desire to chow down.
While this is true to an extent, the simple fact of the matter remains that pure CBD oil with customer-backed qualities is a rarity in the legal hemp marketplace. The vast majority of CBD oil online (even products that are extracted with CO2 technology and "verified" with third-party lab reports), is still subpar in terms of potency, purity, and effectiveness.
Furthermore, a study published in the Journal of Neuroendocrinology has suggested that the ECS is capable of stimulating specific areas of the body involved in metabolism, such as the skeletal muscles and GI tract. This happens due to the presence of anandamide and 2-AG, which are two naturally-occurring compounds in the body that interact with the CB1 and CB2 receptors.
Although CBD oils aren’t regulated by the FDA, purchasing products stateside from one of the nine states where recreational and medical cannabis use is legal will likely result in a higher-quality product than buying one made with hemp-derived CBD oil imported from abroad, says Martin Lee, director of Project CBD, a nonprofit that promotes medical research into CBD.
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